Curated Optogenetic Publication Database

Search precisely and efficiently by using the advantage of the hand-assigned publication tags that allow you to search for papers involving a specific trait, e.g. a particular optogenetic switch or a host organism.

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Recent advances in the use of genetically encodable optical tools to elicit and monitor signaling events.

blue cyan red UV violet BLUF domains Cryptochromes Fluorescent proteins LOV domains Phytochromes UV receptors Review
Curr Opin Cell Biol, 10 Feb 2020 DOI: 10.1016/j.ceb.2020.01.007 Link to full text
Abstract: Cells rely on a complex network of spatiotemporally regulated signaling activities to effectively transduce information from extracellular cues to intracellular machinery. To probe this activity architecture, researchers have developed an extensive molecular tool kit of fluorescent biosensors and optogenetic actuators capable of monitoring and manipulating various signaling activities with high spatiotemporal precision. The goal of this review is to provide readers with an overview of basic concepts and recent advances in the development and application of genetically encodable biosensors and optogenetic tools for understanding signaling activity.
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